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normal bone marrow donors  (Covance)

 
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    Covance normal bone marrow donors
    Normal Bone Marrow Donors, supplied by Covance, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/normal+bone+marrow+donors/pmc06150628-209-95-102?v=Covance
    Average 90 stars, based on 1 article reviews
    normal bone marrow donors - by Bioz Stars, 2026-06
    90/100 stars

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    Image Search Results


    BC275 does not bind to hematopoietic stem and progenitor cells. Freshly isolated T cells (A) and peripheral blood mononuclear cells (PBMCs) (B) were cultured without target cells or with CD33(+) acute myeloid leukemia (AML) line Kasumi-1 in the presence of dilutions of the CD33xCD3 bispecific antibodies (BsAbs) for 1 day with an E:T ratio of 10. The production of Th1 cytokines was measured by a bead-based assay and flow cytometry. The binding of the BsAbs to bone marrow (BM) or cord blood (CB) CD34(+) hematopoietic stem and progenitor cells was assessed by flow cytometry (C). CD33(+) AML cell lines Kasumi-1, MOLM13, and SKM1 were used as positive controls. IFN-γ, interferon-γ; IL, interleukin; TNF-α, tumor necrosis factor-α.

    Journal: Journal for Immunotherapy of Cancer

    Article Title: T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemia

    doi: 10.1136/jitc-2021-002509

    Figure Lengend Snippet: BC275 does not bind to hematopoietic stem and progenitor cells. Freshly isolated T cells (A) and peripheral blood mononuclear cells (PBMCs) (B) were cultured without target cells or with CD33(+) acute myeloid leukemia (AML) line Kasumi-1 in the presence of dilutions of the CD33xCD3 bispecific antibodies (BsAbs) for 1 day with an E:T ratio of 10. The production of Th1 cytokines was measured by a bead-based assay and flow cytometry. The binding of the BsAbs to bone marrow (BM) or cord blood (CB) CD34(+) hematopoietic stem and progenitor cells was assessed by flow cytometry (C). CD33(+) AML cell lines Kasumi-1, MOLM13, and SKM1 were used as positive controls. IFN-γ, interferon-γ; IL, interleukin; TNF-α, tumor necrosis factor-α.

    Article Snippet: Cryopreserved bone marrow (BM) and cord blood (CB)-derived CD34(+) hematopoietic stem and progenitor cells (HSPCs) were purchased from ZenBio (Cat # SER-BMCD34-F and SER-CD34-1F, respectively).

    Techniques: Isolation, Cell Culture, Bead-based Assay, Flow Cytometry, Binding Assay